1. Material specifications for biomedical applications

Two factors need to be taken into account: the biological response of the human body after implant placement (chemical biocompatibility) and the mechanical behavior of the implant (mechanical biocompatibility).

1.1 Chemical biocompatibility of additive elements

Chemical biocompatibility refers to the biological qualities of the implant material. The human body is an aggressive and corrosive environment, due to concentrations of chloride ions and dissolved oxygen. Characterizing the chemical biocompatibility of a material involves assessing its resistance to corrosion, as well as the toxicity of products released into the body. Steinemann has established a classification based on the toxicity of several metallic elements and alloys used in implants. This classification...

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Material specifications for biomedical applications

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Evolution of alloys used

Bibliography

(1) - STEINEMANN (S.) - Corrosion of surgical implants-in vivo and in vitro tests, Evaluation of biomaterials. Advances in biomaterials. - John Wiley and Sons, p. 1-34 (1980).
(2) - WOLFF (J.) - The law of bone remodeling [translated from the 1892 original]...

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Process for the thermomechanical treatment of a titanium alloy, alloy and prosthesis thus obtained. Inventors: LAHEURTE (P.), PRIMA (F.), GLORIANT (T.), ELMAY (W.), EBERHARDT (A.), PATOOR (E.); March 16, 2013, Patent WO 2013/068366 A1.