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Article | REF: AF6818 V1

MRI Contrast Agents

Authors: Jean-François MORFIN, Jean-Claude BELOEIL, Éva TÓTH

Publication date: January 10, 2014, Review date: April 1, 2018

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3. How do contrast agents work?

3.1 Contrast agents and relaxation

The effectiveness of a paramagnetic chelate used as a contrast agent is expressed as relaxivityér 1 or r 2 , with reference to the 1/T 1 or 1/T 2 relaxation velocities of protons in water molecules. The relaxivity of a contrast agent is defined as the paramagnetic increase in the relaxation velocity of water protons normalized by the concentration of this agent

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