Article | REF: K1005 V1

NMR spectra constants

Author: Nicole PLATZER

Publication date: June 10, 1998

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AUTHOR

  • Nicole PLATZER: Engineer from the École nationale supérieure de chimie de Paris (ENSCP) - Professor at Pierre-et-Marie-Curie University - Structural Organic Chemistry Laboratory

 INTRODUCTION

Nuclear magnetic resonance (NMR) spectrometry is a method for studying matter that has been developed in many fields of physics, physical chemistry, chemistry and biology. It concerns both liquid and solid states.

We will focus here on the study of synthetic or naturally-occurring organic molecules and molecules of biological origin in solution, but it is also possible to study inorganic molecules.

The originality of this method applied to solutions is that it gives information on each of the atoms making up the structure under examination, provided that the nucleus of these atoms has a non-zero spin number, on the sequence of atoms in this structure, on the conformation and on the relative configurations. Note that two enantiomers are not differentiated in a non-chiral environment, but can be in a chiral environment.

It reveals interactions between distinct molecules.

It's also an invaluable tool for analyzing molecular movements.

The development of this method for the study of condensed phases is booming, and in many areas the information gathered is becoming as accurate as that obtained in the liquid state.

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NMR spectra constants
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