Article | REF: NM4040 V1

Nanotoxicology and nanomedicine regulation

Authors: Elias FATTAL, Hervé HILLAIREAU

Publication date: April 10, 2020

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3. Interactions with blood compounds and regulatory requirements

The qualitative analysis of serum proteins that associate with particle surfaces has been the subject of numerous studies. Both quantitatively and qualitatively, the richness of nanoparticle-associated proteins results from the large surface area of nanoparticles, as well as from the nature of the surface, its hydrophobicity/hydrophilicity and its chemical composition. . Protein adsorption also depends on particle diameter

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Interactions with blood compounds and regulatory requirements