Article | REF: NM900 V1

Gold nanoparticles

Authors: Olivier PLUCHERY, Marie CARRIERE

Publication date: January 10, 2011

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9. Toxicity of gold nanoparticles

Colloidal gold has long been used in therapy, suggesting that it is biocompatible. However, while many new applications using gold nanoparticles are emerging, uncertainties remain as to their possible impact on living organisms.

9.1 Distribution of gold nanoparticles in organisms: in vivo studies

Studies aimed at characterizing the distribution of gold nanoparticles in organisms following accidental or voluntary exposure (administration for therapeutic purposes) provide two types of information. Firstly, the target organs in which the toxic effects of NPs will be observed can be identified. Secondly, these studies enable the fate of NPs to be correlated with their size, shape, charge and surface functionalization, so that these properties can be modulated to...

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