Article | REF: RE276 V1

Microalgae genome modification for the production of molecules of interest

Authors: Gilles DEFREL, Fayza DABOUSSI

Publication date: June 10, 2019

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4. Genome editing: a revolution in biotechnology

Genome editing is the precise and controlled modification of an organism's genetic heritage, and as such represents a fundamental break with conventional engineering techniques. This has been made possible by the development of molecular scissors capable of recognizing a target sequence and inducing a double-strand break that will be repaired by endogenous double-strand break repair mechanisms (Non homologous end joining (NHEJ) or Homologous Recombination (HR)), resulting in the introduction of mutations, insertion or replacement of a sequence (figure

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Genome editing: a revolution in biotechnology