5. Glossary

DNA, desoxyribonucleic acid; desoxyribonucleic acid

Macromolecule carrying genetic information, formed by the concatenation of nucleotides, themselves made up of a nucleic base (adenine, guanine, thymine, cytosine), a phosphate group and a sugar (deoxyribose).

RNA, ribonucleic acid; ribonucleic acid

Macromolecule similar to DNA where the sugar is a ribose.

CCD, dynamic combinatorial chemistry

Dynamic combinatorial chemistry is an extension of combinatorial chemistry, in which the various elements of a mixture in solution combine reversibly via covalent or non-covalent bonds. The constitution of reaction mixtures, i.e. the proportion of each possible combination, is imposed by the equilibria involved and by the operating conditions. This is referred to as a dynamic...

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Bibliography

(1) - WATSON (J.D.), CRICK (F.H.C.) - Nature. - 171, 737-738 (1953).
(2) - KENDREW (J.C.), BODO (G.), DINTZIS (H.M.), PARRISH (R.G.), WYCKOFF (H.), PHILLIPS (D.C.) - Nature. - 181, 662-666 (1958).
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Software tools

Visualization of complex molecular structures (proteins, polynucleotides): the NGL Viewer :

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. Web-based molecular graphics for large complexes. Bioinformatics: bty 419, 2018.doi :10.1093bioinformatics/bty 419

AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res...