4. Optimizing solid-phase microextraction

When developing a preconcentration method using solid-phase microextraction, several parameters need to be optimized:

extraction mode ;
the nature of the polymer ;
the time required to achieve equilibrium in compound distribution between matrix and polymer;
the desorption time of polymer compounds.

4.1 Extraction mode selection

The choice is between direct or headspace extraction. The efficiency of each technique depends on the physico-chemical characteristics of the compounds to be extracted and the nature of the matrix. In general, for liquid matrices, direct extraction is more sensitive, but the...

You do not have access to this resource.

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource.
Click here to request your free trial access!

Already subscribed? Log in!

The Ultimate Scientific and Technical Reference

A Comprehensive Knowledge Base, with over 1,200 authors and 100 scientific advisors

+ More than 10,000 articles and 1,000 how-to sheets, over 800 new or updated articles every year

From design to prototyping, right through to industrialization, the reference for securing the development of your industrial projects

This article is included in

Analysis and Characterization

This offer includes:

Knowledge Base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

Practical Path

Operational and didactic, to guarantee the acquisition of transversal skills

Doc & Quiz

Interactive articles with quizzes, for constructive reading

Subscribe now!

Ongoing reading
Optimizing solid-phase microextraction

Previous
page Implementation

Advantages and disadvantages

Bibliography

(1) - PAWLISZYN (J.) - Solid phase microextraction : theory and practice. - Wiley-VCH, New York (1997).
(2) - PAWLISZYN (J.) - Applications of solid phase microextractions. - Royal Society of Chemistry, Londres...