Article | REF: P1470 V1

Chiral separations by LC, SPC and GPC

Authors: Marcel CAUDE, Nathalie BARGMANN-LEYDER

Publication date: March 10, 2001

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5. Conclusion

The multiplicity of CSPs on the market is both a handicap (difficult choice) and a strength (possibility of solving all problems). There is no simple rule for choosing a CSP, especially as the choice is rarely unequivocal. However, we can propose a separation strategy based on the racemate structure (number and polarity of functional groups near its center of asymmetry, steric hindrance and conformational flexibility) [116] (figure 19...

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