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2. Validation vocabulary
The term "validation" is widely used in the analytical literature. Because of this high frequency, there are many different meanings and a certain ambiguity about its use. Since a choice had to be made, we'll start with the definitions proposed in the VIM , recalled here.
Measurand (VIM 2.3): quantity to be measured.
Measurement uncertainty (VIM 2.26): non-negative parameter characterizing the dispersion of values attributed to a measurand, based on the information used.
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Validation vocabulary
Estimation of method reliability
Bibliography
Software tools
There are few software packages dedicated to method validation. Arlenda ( http://www.arlenda.com/ ) has developed one called "e-noval®". It uses the accuracy profile and produces a certified report. Its originality lies in the fact that it operates via the Internet (Web-based solution): the user copies the data into an Internet interface,...
Websites
AOAC (Association of Official Analytical Chemists): originally American, this association of analysts has become international. In addition to its standardizing role, it validates methods according to various protocols http://www.aoac.org/
EURACHEM, a network of European organizations whose aim is to set up a forum for the traceability...
Standards and norms
Association française de normalisation Afnor
- Water quality – Protocol for initial assessment of method performance in a laboratory - NF T90-210 - 2009
- Exigences générales concernant la compétence des laboratoires d'étalonnages et d'essais - NF EN ISO/CEI 17025 - 2005
- Laboratoires d'analyses de biologie médicale....
International Organization for standardization ISO
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