Article | REF: SL290 V2

Qualification of analytical instruments

Authors: Huguette FABRE, Marie-Dominique BLANCHIN, Catherine PERRIN

Publication date: June 10, 2016

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5. Maintenance and calibration

After installation and qualification, all equipment must be subject to a planned maintenance and calibration program.

Calibration involves determining the deviation of the device using reference materials, preferably certified. It should always be carried out before the OQ/PQ. It is often followed by adjustment.

Preventive maintenance involves planned servicing of equipment, with checkpoints and replacement of parts. It reduces the risk of breakdowns by detecting problems before they occur, and helps extend the life of the equipment.

Calibration and preventive maintenance are carried out at a specific frequency, depending on the instrument, its environment and use, and must be documented. Following these operations, a qualification label is affixed to the instrument, indicating...

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