Français
3. Processes to generate liposomes
3.1 Introduction to liposomes
Liposomes are spherical vesicles composed of an aqueous core (intravesicular medium) and a membrane formed by one or several phospholipid bilayers. As phospholipids are amphiphilic, in the presence of water they spontaneously organize themselves so that the polar heads (phosphate groups) interact with water, and the hydrophobic tails (long hydrocarbon chains) are grouped together. This results in a structure that can encapsulate hydrophilic substances (in the aqueous core) together with hydrophobic substances (in the bilayer) or amphiphilic substances. As active ingredient vectors they are of great interest because:
they are non-toxic;
...
The Ultimate Scientific and Technical Reference
This article is included in
Drugs and pharmaceuticals
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Processes to generate liposomes
Impregnation processes
Bibliographic references
Patents
BOUTIN (O.). – Apparatus for forming particles of a target substance . US Patent 11/846,664 (2007).
CALDERONE (M.), RODIER (E.) et FORMULCOAT. – Procédé d’enrobage de poudres . Pub. FR 10.03.2006, WO2006/030112 (2006).
CASTOR (T.P.). – Methods and apparatus for making liposomes...
Directory
Manufacturers, Service providers
A3I : dispositifs expérimentaux haute pression thermo régulés : études et réalisations http://www.a3i-cer.fr
SEPAREX : installations haute pression http://www.separex.fr
...
The Ultimate Scientific and Technical Reference
