Article | REF: CHV4010 V1

Forming processes of pharmaceutical active principles in supercritical phase

Author: Elisabeth BADENS

Publication date: September 10, 2017, Review date: December 5, 2016

You do not have access to this resource.
Click here to request your free trial access!

Already subscribed? Log in!


Français

3. Processes to generate liposomes

3.1 Introduction to liposomes

Liposomes are spherical vesicles composed of an aqueous core (intravesicular medium) and a membrane formed by one or several phospholipid bilayers. As phospholipids are amphiphilic, in the presence of water they spontaneously organize themselves so that the polar heads (phosphate groups) interact with water, and the hydrophobic tails (long hydrocarbon chains) are grouped together. This results in a structure that can encapsulate hydrophilic substances (in the aqueous core) together with hydrophobic substances (in the bilayer) or amphiphilic substances. As active ingredient vectors they are of great interest because:

  • they are non-toxic;

  • ...

You do not have access to this resource.

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource.
Click here to request your free trial access!

Already subscribed? Log in!


The Ultimate Scientific and Technical Reference

A Comprehensive Knowledge Base, with over 1,200 authors and 100 scientific advisors
+ More than 10,000 articles and 1,000 how-to sheets, over 800 new or updated articles every year
From design to prototyping, right through to industrialization, the reference for securing the development of your industrial projects

This article is included in

Drugs and pharmaceuticals

This offer includes:

Knowledge Base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

Practical Path

Operational and didactic, to guarantee the acquisition of transversal skills

Doc & Quiz

Interactive articles with quizzes, for constructive reading

Subscribe now!

Ongoing reading
Processes to generate liposomes