4. Conclusion and outlook
As we have tried to show in this article, multicomponent reactions are currently enjoying considerable growth, as they are perfectly in line with the development of more environmentally-friendly chemistry. The examples we have chosen to illustrate our point also show the tremendous potential of transition metal-catalyzed processes for the discovery of new one-pot reactions, with these new methodologies enabling a combination of complexity – diversity, impossible with traditional chemistry. New ways of accessing complex and varied systems quickly, efficiently, elegantly and cleverly have thus been developed. There is no doubt that new innovative processes will continue to emerge from this extremely stimulating field of research, and that asymmetric catalysis in particular will see increasing development.
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Conclusion and outlook
Bibliography
Other works
ISAMBERT (N.) and LAVILLA (R.) – Heterocycles as key substrates in multicomponent reactions: the fast lane toward molecular complexity. Chem. Eur. J., 14, p. 8444-8454 (2008).
ULACZYK-LESANLO (A.) and HALL (D.G.) – New multicomponent reactions for generating libraries of polycyclic natural products. Curr. Opin. Chem. Biol. 9, pp. 266-276 (2005).
GANEM (B.) – Strategies for...
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