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5. Hydrodynamics and material transfer in cytocultivators
5.1 Hydrodynamics
The hydrodynamics of cytocultivators are broadly similar to those of gas-liquid stirred reactors, but with "gentle" stirring and aeration conditions. Agitation should ensure proper suspension of cells or microcarriers, homogenization of the liquid phase to limit any concentration gradients, reduced mixing times and increased material transfer capacities (O 2 and nutrients). However, as animal cells are reputed to be fragile,...
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Hydrodynamics and material transfer in cytocultivators
Conclusion
Bibliography
Websites
LEEM study. Bioproduction in 2008: state of play and recommendations for French attractiveness. http://www.leem.org/dossier/101/etude-bioproduction-en-2008-etat-des-lieux-et-recommandations-pour-l-attractivite-1297.htm
Events (non-exhaustive list)
ESACT Congress, held every two years in Europe http://www.esact.org/meetings_esact.html
Congress of the engineering foundation: cell culture engineering, held every two years, mainly in the U.S.
Directory
Organizations – Federations – Associations (non-exhaustive list)
ESACT Association: European Society of Animal Cell Technology http://www.esact.org/
Association ACTIP: Animal Cell Technology Industrial Platform http://www.actip.org/
Training courses...
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