Article | REF: NM4040 V1

Nanotoxicology and nanomedicine regulation

Authors: Elias FATTAL, Hervé HILLAIREAU

Publication date: April 10, 2020

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2. Descriptive elements of a nanomedicine

Beyond definition, the most important elements in understanding the in vivo fate and deleterious effects of nanomedicines are their physico-chemical characteristics: composition, diameter, mean diameter, particle size distribution and aggregation, morphology, zeta potential, crystallinity, rigidity/deformability and molecular organization.

2.1 Composition

The most important property concerns the biodegradability of the material making up the heart of the drug. Lipids, polymers, which can be synthetic or biopolymers, are therefore preferred.

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Descriptive elements of a nanomedicine