2. Development of EnFET enzymatic field-effect transistors

Adapting ChemFET technology to the detection of biochemical species in solution has required the use of enzymes. Through an active site in their molecular structure, these proteins are able to catalyze chemical or biochemical reactions by lowering their activation energy. Thus, in the presence of a given enzyme, one or more specific substrates will be transformed into one or more products according to the enzymatic biocatalysis reaction scheme:

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Development of EnFET enzymatic field-effect transistors

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Bibliography

(1) - BERGVELD (P.) - Development of an ion-sensitive solid-state device for neurophysiological measurements. - IEEE Transactions on Biomedical Engineering, BME-17, p. 102-105 (1970).
(2) - SKOTNICKI (T.) - Transistor MOS et sa technologie de fabrication....