Article | REF: RE218 V1

Silk nanofibers-based biomaterials for biomedical applications

Authors: Guillaume VIDAL, Tony DINIS, Christophe EGLES

Publication date: April 10, 2013

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4. Different forms of silk matrices used in biomedical applications

Material preparation is based on regenerating fibroin by forcing or promoting its self-assembly from aqueous or non-aqueous solutions. Fibroin solubilization damages the secondary crystalline structure, but retains the integrity of its primary structure, enabling different material morphologies to be obtained.

4.1 Films

Films are generally prepared by slow evaporation of a solvent. The solvent may be aqueous or non-aqueous, depending on the intended use and application of the silk biomaterial. The films obtained can then be processed by chemical or structural modifications ...

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Different forms of silk matrices used in biomedical applications