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6. Conclusion
A better understanding of many biological mechanisms requires modeling methods and tools dedicated to the study of the mechanical behavior of the cellular cytoskeleton. Tensegrity systems have demonstrated their relevance and effectiveness in this respect. They are capable of representing the complex architecture of the cytoskeleton in a biorealistic way, offer the possibility of modeling its structuring process during cell adhesion, and have assembly properties that enable the generation of multicellular tissues.
The results of numerical simulations based on this analogy are validated by the majority of experimental observations, reflecting the potential of this approach and pointing the way to future advances.
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Bibliography
Software tools
LMGC90 software is a development platform dedicated to modeling interaction problems, such as granular materials and block buildings. Bodies can be rigid or deformable (discrete elements, finite elements with multi-physics coupling) and interactions can be of any nature (contact, friction, cohesion, etc.). It consists of a library of components (modules) that can be used via a macro language, relying as far as possible...
Patents
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SNELSON (K.). – Continuous tension, discontinuous compression structures. US Patent, n° 3, 169, p. 611 (1965).
FULLER (R.B.). – Tensile Integrity Structures. US Patent n° 3, 063, p. 521 (1962).
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